Our lab is generally interested in manipulating images to extract information of physiologic importance. Our core skills include: within and across subject image registration, creating quantitatively accurate images, extracting regional information from raw data (time activity curves, spatial measurements), applying kinetic models, and the interactive display of images. 

Our current areas of focus cover three broad areas: neuroscience, oncology, and cardiology. The above skills are being applied to: critically evaluate new radiotracers in collaboration with the Radiopharmaceutical Discovery Lab, provide physiologic parameters (measure neuro receptor and transporter density, estimate beta amyloid protein density in the brain, calculate amino acid uptake rate, measure neuro, cardiac, and renal blood flow), perform quality assessment of PET data, correct for patient motion in cardiac and neuro PET studies, calculate radiodosimetry for new compounds, critically evaluate the next generation of cameras, and provide real time guidance for collecting biopsy samples.